@font-face{font-family:Instrument Sans Variable;font-style:normal;font-display:swap;font-weight:400 700;src:url(/_astro/instrument-sans-latin-ext-wght-normal.B5bTHO_g.woff2)format("woff2-variations");unicode-range:U+100-2BA,U+2BD-2C5,U+2C7-2CC,U+2CE-2D7,U+2DD-2FF,U+304,U+308,U+329,U+1D00-1DBF,U+1E00-1E9F,U+1EF2-1EFF,U+2020,U+20A0-20AB,U+20AD-20C0,U+2113,U+2C60-2C7F,U+A720-A7FF}@font-face{font-family:Instrument Sans Variable;font-style:normal;font-display:swap;font-weight:400 700;src:url(/_astro/instrument-sans-latin-wght-normal.BbzFLZTg.woff2)format("woff2-variations");unicode-range:U+??,U+131,U+152-153,U+2BB-2BC,U+2C6,U+2DA,U+2DC,U+304,U+308,U+329,U+2000-206F,U+20AC,U+2122,U+2191,U+2193,U+2212,U+2215,U+FEFF,U+FFFD}@font-face{font-family:Instrument Serif;font-style:normal;font-display:swap;font-weight:400;src:url(/_astro/instrument-serif-latin-ext-400-normal.C2je3j2s.woff2)format("woff2"),url(/_astro/instrument-serif-latin-ext-400-normal.CFCUzsTy.woff)format("woff");unicode-range:U+100-2BA,U+2BD-2C5,U+2C7-2CC,U+2CE-2D7,U+2DD-2FF,U+304,U+308,U+329,U+1D00-1DBF,U+1E00-1E9F,U+1EF2-1EFF,U+2020,U+20A0-20AB,U+20AD-20C0,U+2113,U+2C60-2C7F,U+A720-A7FF}@font-face{font-family:Instrument Serif;font-style:normal;font-display:swap;font-weight:400;src:url(/_astro/instrument-serif-latin-400-normal.DnYpCC2O.woff2)format("woff2"),url(/_astro/instrument-serif-latin-400-normal.BVbkICAY.woff)format("woff");unicode-range:U+??,U+131,U+152-153,U+2BB-2BC,U+2C6,U+2DA,U+2DC,U+304,U+308,U+329,U+2000-206F,U+20AC,U+2122,U+2191,U+2193,U+2212,U+2215,U+FEFF,U+FFFD}@font-face{font-family:Newsreader Variable;font-style:normal;font-display:swap;font-weight:200 800;src:url(/_astro/newsreader-vietnamese-opsz-normal.BjhtXyW2.woff2)format("woff2-variations");unicode-range:U+102-103,U+110-111,U+128-129,U+168-169,U+1A0-1A1,U+1AF-1B0,U+300-301,U+303-304,U+308-309,U+323,U+329,U+1EA0-1EF9,U+20AB}@font-face{font-family:Newsreader Variable;font-style:normal;font-display:swap;font-weight:200 800;src:url(/_astro/newsreader-latin-ext-opsz-normal.BQn1nviT.woff2)format("woff2-variations");unicode-range:U+100-2BA,U+2BD-2C5,U+2C7-2CC,U+2CE-2D7,U+2DD-2FF,U+304,U+308,U+329,U+1D00-1DBF,U+1E00-1E9F,U+1EF2-1EFF,U+2020,U+20A0-20AB,U+20AD-20C0,U+2113,U+2C60-2C7F,U+A720-A7FF}@font-face{font-family:Newsreader Variable;font-style:normal;font-display:swap;font-weight:200 800;src:url(/_astro/newsreader-latin-opsz-normal.s-izfB6B.woff2)format("woff2-variations");unicode-range:U+??,U+131,U+152-153,U+2BB-2BC,U+2C6,U+2DA,U+2DC,U+304,U+308,U+329,U+2000-206F,U+20AC,U+2122,U+2191,U+2193,U+2212,U+2215,U+FEFF,U+FFFD}:root{--header:#12284a;--page:#fbfcfd;--text:#121d2f;--muted:#2a3240;--muted-2:#5b6472;--label:#38414f;--planned:#6b7480;--border:#d9dee4;--band:#f4f6f8;--footer:#edf0f3;--accent:#1e3f7a;--nav-link:#c9d1dc;--underline:#aab3be;--serif-display:"Instrument Serif", Georgia, serif;--serif-body:"Newsreader Variable", "Newsreader", Georgia, serif;--sans:"Instrument Sans Variable", "Instrument Sans", system-ui, sans-serif}*,:before,:after{box-sizing:border-box}body{background:var(--page);color:var(--text);font-family:var(--serif-body);-webkit-text-size-adjust:100%;margin:0}::selection{color:var(--text);background:#d5deec}@media (prefers-reduced-motion:no-preference){html{scroll-behavior:smooth}}h1,h2{text-wrap:balance}p{text-wrap:pretty}a{color:var(--text);text-underline-offset:.22em;text-decoration-thickness:1px;text-decoration-color:var(--underline);transition:color .15s,text-decoration-color .15s}a:hover{color:var(--muted);text-decoration-color:currentColor}a:focus-visible,button:focus-visible{outline:2px solid var(--accent);outline-offset:3px}.skip-link{z-index:20;min-height:44px;color:var(--text);font-family:var(--sans);background:#fff;align-items:center;padding:0 16px;font-size:15px;font-weight:600;display:inline-flex;position:absolute;top:-100px;left:32px}.skip-link:focus{top:8px}.arrow{vertical-align:-.08em;display:inline-block}.wrap{max-width:1200px;margin:0 auto;padding-left:32px;padding-right:32px}.section{padding-top:64px;padding-bottom:64px}.site-header{background:var(--header);color:#f4f6f8;position:relative}.site-header .wrap{flex-wrap:wrap;justify-content:space-between;align-items:center;gap:16px;padding-top:10px;padding-bottom:10px;display:flex}.brand{color:#fff;align-items:center;min-height:44px;text-decoration:none;display:flex}.brand:hover{color:#fff}.lockup{white-space:nowrap;align-items:center;gap:14px;display:inline-flex}.lockup-mark{flex:none;display:block}.lockup-name{flex-direction:column;align-items:center;display:inline-flex}.wordmark{font:400 25px / 1 var(--serif-display);letter-spacing:.005em}.wordmark-research{font:400 10px / 1 var(--serif-display);letter-spacing:.38em;text-transform:uppercase;margin-top:3px;margin-right:-.38em}.site-header a:focus-visible,.site-header button:focus-visible{outline-color:var(--nav-link)}.nav-links{font-family:var(--sans);flex-wrap:wrap;gap:4px 28px;margin:0;padding:0;font-size:15px;list-style:none;display:flex}.nav-links a{color:var(--nav-link);padding:12px 0;text-decoration:none;display:block}.nav-links a:hover{color:#fff}.nav-links a[aria-current=page]{color:#fff;text-underline-offset:.4em;text-decoration:underline}.menu-button{color:#f4f6f8;cursor:pointer;background:0 0;border:0;justify-content:center;align-items:center;width:44px;height:44px;margin-right:-10px;padding:0;display:none}.menu-button svg{display:block}.menu-button .close,.site-header.is-open .menu-button .open{display:none}.site-header.is-open .menu-button .close{display:block}@media (width<=760px){.js .menu-button{display:inline-flex}.js .site-nav{z-index:10;background:var(--header);border-top:1px solid #c9d1dc2e;display:none;position:absolute;top:100%;left:0;right:0;box-shadow:0 12px 24px #12284a2e}.js .site-header.is-open .site-nav{display:block}.js .nav-links{flex-flow:column;gap:0;padding:4px 32px 12px;font-size:16px}.js .nav-links a{align-items:center;min-height:48px;padding:0;display:flex}.js .nav-links li+li a{border-top:1px solid #c9d1dc24}}.label{font-family:var(--sans);letter-spacing:.12em;text-transform:uppercase;color:var(--label);align-items:center;gap:11px;font-size:14px;font-weight:600;display:flex}.label:before{content:"";background:var(--accent);width:4px;height:16px;display:inline-block}h2,.about h1{font-family:var(--serif-display);margin:11px 0 0;font-size:42px;font-weight:400;line-height:1.1}.hero-band{background:var(--band)}.hero{padding-top:43px;padding-bottom:43px}.hero-plot{display:none}.hero-plot-null{stroke:#d3d6da;stroke-width:2px}.hero-plot-ci{fill:none;stroke:#a5adb9;stroke-width:2.5px}.hero-plot-point{fill:#5a6575}.hero-plot-point.lead{fill:var(--header)}@media (width>=761px){.hero{grid-template-columns:minmax(0,1.25fr) minmax(0,1fr);align-items:center;gap:40px;display:grid}.hero-plot{justify-self:end;width:100%;max-width:385px;height:auto;display:block}}.hero h1{max-width:15ch;font-family:var(--serif-display);letter-spacing:-.01em;margin:0;font-size:clamp(46px,5.5vw,69px);font-weight:400;line-height:.955}.hero p{max-width:37.5rem;color:var(--muted);margin:17px 0 0;font-size:21px;line-height:1.39}.lede{max-width:42rem;color:var(--muted);margin:12px 0 0;font-size:19px;line-height:1.55}.cards{grid-template-columns:repeat(auto-fill,minmax(min(300px,100%),1fr));gap:18px;margin-top:29px;display:grid}.card{border:1px solid var(--border);min-width:0;color:var(--text);background:#fff;flex-direction:column;gap:12px;padding:23px 26px 21px;text-decoration:none;display:flex}a.card{transition:border-color .15s}a.card:hover{color:var(--text);border-color:var(--text)}a.card:active{background:var(--band)}a.card:hover .card-foot{text-underline-offset:.22em;text-decoration:underline 1px}.card-head{flex-wrap:wrap;align-items:center;gap:8px 13px;display:flex}.card-name{min-width:0;font:400 clamp(22px, 6.4vw, 27.5px) / 1.1 var(--serif-display);letter-spacing:.005em;margin:0}.card p{color:var(--muted);text-wrap:wrap;margin:0;font-size:16.5px;line-height:24px}.card-foot{font-family:var(--sans);color:var(--text);align-self:flex-end;margin-top:auto;padding-top:4px;font-size:14px;font-weight:600}.foot-short{display:none}.card-foot.soon{letter-spacing:.1em;text-transform:uppercase;color:var(--muted-2);font-size:13px}.planned{border-top:1px solid #e6e9ee;margin-top:32px;padding-top:20px}.planned-toggle{cursor:pointer;min-height:44px;font-family:var(--sans);letter-spacing:.1em;text-transform:uppercase;color:var(--muted);background:0 0;border:0;align-items:center;gap:10px;padding:0;font-size:13px;font-weight:600;display:flex}html:not(.js) .planned-toggle{cursor:default;pointer-events:none}html:not(.js) .planned-toggle svg{display:none}.planned-toggle:hover{color:var(--text)}.planned-toggle .count{color:var(--muted-2)}.planned-toggle svg{transition:transform .2s}.planned-toggle[aria-expanded=true] svg{transform:rotate(180deg)}.planned-list{color:var(--planned);margin:8px 0 0;padding:0;list-style:none}.js .planned:not(.is-open) .planned-list{display:none}.planned-row{border-top:1px solid var(--border);grid-template-columns:32px minmax(0,1fr);align-content:start;align-items:center;column-gap:12px;padding:11px 0;display:grid}.planned-name{min-width:0;font:400 18px / 1.15 var(--serif-display);letter-spacing:.005em;overflow-wrap:anywhere}.planned-row p{grid-column:2;margin:2px 0 0;font-size:14px;line-height:1.4}@media (width>=700px){.planned-list{grid-template-columns:repeat(2,minmax(0,1fr));grid-template-rows:repeat(var(--rows), auto);grid-auto-flow:column;column-gap:32px;display:grid}}.band{background:var(--band)}.steps{grid-template-columns:minmax(0,1fr);gap:32px;margin-top:28px;display:grid}@media (width>=760px){.steps{grid-template-columns:repeat(3,minmax(0,1fr));gap:28px}}@media (width>=1000px){.steps{gap:40px}}.step{border-top:1px solid var(--text);min-width:0;padding-top:24px}.step-number{font-family:var(--serif-display);color:var(--accent);font-size:28px;line-height:1}.step h3{font-family:var(--sans);margin:16px 0 0;font-size:18px;font-weight:600}.step p{color:var(--muted);margin:8px 0 0;font-size:16.5px;line-height:1.5}.about p.bio{max-width:42rem;color:var(--muted);margin:12px 0 0;font-size:19px;line-height:1.55}.about-page h2{margin-top:48px;font-size:32px}.orcid{font-family:var(--sans);color:var(--label);margin:16px 0 0;font-size:15px}.orcid a{padding:10px 0;display:inline-block}.more-link{font-family:var(--sans);color:var(--label);margin:12px 0 0;font-size:15px}.more-link a{align-items:center;gap:6px;min-height:44px;display:inline-flex}.steps+.more-link{margin-top:20px}.method{grid-template-columns:minmax(0,1fr);gap:12px;display:grid}.section+.section.method{padding-top:0}.method h2{margin:0;font-size:32px}.method-body>:first-child{margin-top:0}.method-body p,.method-body li{color:var(--muted);max-width:42rem;font-size:19px;line-height:1.55}.method-body p{margin:12px 0 0}.method-body h3{font-family:var(--sans);margin:28px 0 0;font-size:18px;font-weight:600}.method-body ul{margin:12px 0 0;padding-left:20px}.method-body li+li{margin-top:6px}.specialty-list{max-width:42rem;font-family:var(--sans);margin:0;padding:0;font-size:15px;list-style:none}.specialty-row{border-top:1px solid var(--border);grid-template-columns:minmax(0,13rem) auto auto;justify-content:start;align-items:center;column-gap:20px;display:grid}.specialty-row a{align-items:center;min-height:44px;display:inline-flex}.specialty-name{min-width:0;font:400 18px / 1.15 var(--serif-display);letter-spacing:.005em;overflow-wrap:anywhere}.site-footer{background:var(--footer);font-family:var(--sans)}.site-footer .wrap{padding-top:64px;padding-bottom:40px}.footer-cols{flex-wrap:wrap;justify-content:space-between;gap:40px;display:flex}.footer-brand{flex:280px;min-width:0}.footer-brand .lockup{color:var(--text);gap:21px}.footer-brand .lockup-mark{width:51px;height:24px}.footer-brand .wordmark{font-size:37.5px}.footer-brand .wordmark-research{margin-top:4.5px;font-size:15px}.footer-brand p{color:var(--label);margin:16px 0 0;font-size:15px;line-height:1.6}.footer-col{flex:200px;min-width:0}.footer-heading{letter-spacing:.1em;text-transform:uppercase;color:var(--muted-2);font-size:13px;font-weight:600}.footer-col p{margin:12px 0 0;font-size:15px}.footer-col .footer-note{max-width:22rem;color:var(--label);line-height:1.5}.footer-bottom{color:var(--muted-2);border-top:1px solid #d3d9e0;margin-top:48px;padding-top:20px;font-size:13px}@media (width<=760px){.footer-col p a{align-items:center;min-height:44px;display:inline-flex}.orcid a{align-items:center;min-height:44px;padding:0;display:inline-flex}}@media (width<=600px){.wrap,.js .nav-links{padding-left:20px;padding-right:20px}.skip-link{left:20px}.hero h1{font-size:clamp(44px,12vw,46px)}.hero p{font-size:19px}h2,.about h1{font-size:32px}.lede,.about p.bio,.method-body p,.method-body li{font-size:16.5px}.method h2,.about-page h2{font-size:26px}.specialty-row{grid-template-columns:auto auto;padding-top:10px}.specialty-name{grid-column:1/-1}.cards{gap:0;margin-top:22px}.card{flex-direction:row;justify-content:space-between;align-items:center;gap:10px;min-height:52px;padding:8px 14px}.card+.card{border-top:0}.card p{display:none}.card-head{flex-wrap:nowrap;gap:10px;min-width:0}.card .mark{width:38px;height:16px}.card-name{font-size:21px}.card-foot{flex:none;align-self:center;margin:0;padding:0}.card-foot.soon{letter-spacing:.06em;font-size:12px}.foot-long{display:none}.foot-short{display:inline}.planned{margin-top:20px;padding-top:8px}.planned-list{grid-template-columns:repeat(2,minmax(0,1fr));grid-template-rows:repeat(var(--rows), auto);grid-auto-flow:column;column-gap:16px;display:grid}.planned-row{grid-template-columns:20px minmax(0,1fr);column-gap:8px;padding:7px 0}.planned-row .mark{width:20px;height:9px}.planned-name{font-size:16px}.planned-row p{display:none}}@media (prefers-reduced-motion:reduce){*{transition:none!important}}